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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHTF18
All Species:
13.94
Human Site:
S135
Identified Species:
23.59
UniProt:
Q8WVB6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVB6
NP_071375.1
975
107383
S135
T
D
I
T
P
P
P
S
P
E
D
L
A
E
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087813
975
107675
S135
M
D
I
T
P
P
P
S
P
E
D
L
V
E
L
Dog
Lupus familis
XP_547205
952
105405
S111
E
L
W
P
E
G
P
S
D
A
A
A
D
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIW9
969
108119
S129
G
D
I
T
P
P
P
S
P
E
V
F
P
E
M
Rat
Rattus norvegicus
NP_001099243
968
107973
S129
G
D
I
T
P
P
P
S
P
E
V
F
P
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519056
506
55652
Chicken
Gallus gallus
XP_414833
951
106607
S121
T
P
V
P
G
S
A
S
P
R
G
P
H
A
V
Frog
Xenopus laevis
Q6NU40
1000
113204
P144
S
D
D
I
T
P
P
P
S
P
N
H
S
P
K
Zebra Danio
Brachydanio rerio
NP_001103572
957
108656
R128
R
E
V
R
D
G
P
R
F
S
L
T
L
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_787969
993
111731
A144
G
L
E
K
E
N
A
A
A
N
Q
L
Q
E
V
Honey Bee
Apis mellifera
XP_001122463
755
86984
P63
V
Y
K
E
L
N
I
P
T
S
N
K
Y
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780624
1005
112781
K139
T
P
P
P
T
P
N
K
D
E
L
G
Q
F
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_171966
954
107988
E121
K
E
V
V
H
V
M
E
E
E
E
E
V
V
I
Baker's Yeast
Sacchar. cerevisiae
P49956
741
84355
T48
F
V
S
S
T
G
E
T
V
Q
L
K
K
K
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
73
N.A.
76
77.2
N.A.
20.2
53.7
53.4
46.6
N.A.
32.4
27.8
N.A.
34.6
Protein Similarity:
100
N.A.
95.9
79.6
N.A.
81.7
82.7
N.A.
29.8
68.7
71
63.3
N.A.
52.5
45.3
N.A.
54.1
P-Site Identity:
100
N.A.
86.6
13.3
N.A.
66.6
66.6
N.A.
0
20
20
6.6
N.A.
13.3
0
N.A.
20
P-Site Similarity:
100
N.A.
86.6
13.3
N.A.
73.3
73.3
N.A.
0
33.3
40
20
N.A.
26.6
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
8
8
8
8
8
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
36
8
0
8
0
0
0
15
0
15
0
8
0
0
% D
% Glu:
8
15
8
8
15
0
8
8
8
43
8
8
0
36
8
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
0
15
0
8
0
% F
% Gly:
22
0
0
0
8
22
0
0
0
0
8
8
0
8
15
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% H
% Ile:
0
0
29
8
0
0
8
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
8
8
0
0
0
8
0
0
0
15
8
8
8
% K
% Leu:
0
15
0
0
8
0
0
0
0
0
22
22
8
0
15
% L
% Met:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
15
% M
% Asn:
0
0
0
0
0
15
8
0
0
8
15
0
0
8
0
% N
% Pro:
0
15
8
22
29
43
50
15
36
8
0
8
15
8
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
15
0
0
% Q
% Arg:
8
0
0
8
0
0
0
8
0
8
0
0
0
0
0
% R
% Ser:
8
0
8
8
0
8
0
43
8
15
0
0
8
8
0
% S
% Thr:
22
0
0
29
22
0
0
8
8
0
0
8
0
0
0
% T
% Val:
8
8
22
8
0
8
0
0
8
0
15
0
15
8
15
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _